📄 Category

psychiatry and clinical psychology

186 papers

Understanding the human mind and treating mental health conditions requires a deep blend of biological insight and behavioral science. This category explores the cutting-edge research shaping how we diagnose and treat psychiatric disorders, from depression and anxiety to complex neurological conditions. Here, you will find the latest discoveries that bridge the gap between clinical observation and molecular mechanisms, offering fresh perspectives on patient care and therapeutic innovation.

Gist.Science brings these vital studies directly to you by monitoring medRxiv, the leading preprint server for health sciences. As soon as new manuscripts appear in this field, our team processes them to provide both accessible plain-language summaries and detailed technical overviews. This ensures that complex findings are understandable for everyone, from curious readers to busy professionals who need quick, accurate insights without wading through dense academic prose.

Below are the most recent psychiatry and clinical psychology preprints, curated and summarized to keep you informed on the evolving landscape of mental health research.

📄 psychiatry and clinical psychology

Level of Preparedness to Use Psilocybin Among Individuals Seeking Psychedelic Risk Reduction: A retrospective study of a pilot psychiatric consultation service

This retrospective study of 29 patients in an Oregon pilot psychiatric consultation service reveals that individuals seeking psilocybin risk reduction support typically have high baseline preparedness, a history of trauma and prior psychedelic use, and diverse motivations for seeking care, highlighting the emerging role of healthcare systems in providing evidence-based education and risk management as interest in psychedelics grows.

Harrison, H. V., Gaillard, M., Cook, R. R., Sarparast, A., Levander, X. A.2026-08-19
📄 psychiatry and clinical psychology

Damped Physical Activity and Unstable Sleep: Fitbit-Derived Rest-Activity Phenotypes in Inter-episode Mood Disorders

Analyzing Fitbit data from over 28,000 participants in the All of Us Research Program, this study reveals that inter-episode mood disorders (MDD and BD) are characterized by a shared continuum of disturbances where physical activity is reduced and rigid while sleep is highly unstable, with variability metrics capturing residual symptoms better than mean-level measures.

Corponi, F., Reami, M., Ossola, P., Fanelli, G., Jauhar, S., Wyse, C., Young, A. H.2026-08-18
📄 psychiatry and clinical psychology

Antiestrogenic therapy effect on brain structure and mental health in women with breast cancer: a longitudinal MRI study

In a longitudinal study of women with breast cancer initiating antiestrogen therapy, no robust short-term macrostructural brain changes were detected over 2–3 weeks, though the treatment group exhibited a significant increase in somatic depressive symptoms compared to healthy controls.

Yazici Sarikaya, S., Guelbahce, B., Kimmig, A. C. S., Brucker, S. Y., Bender, B., Hoopmann, U., Hahn, M., Wikman, A., De (…)2026-08-17
📄 psychiatry and clinical psychology

Seeking Help from Chatbots for Suicide Thoughts: Associations with Other Help Seeking Sources and Mental Health Symptoms

This study of individuals with clinically significant depression or anxiety reveals that intentions to seek help for suicide thoughts from chatbots are generally lower than from traditional informal or formal sources, appear largely independent of those other channels, and are uniquely associated with higher anxiety severity and specific relationship dynamics.

Heo, R., McBride, L., Parrish, E., Fulginiti, A., Taylor, C., Depp, C.2026-08-14
📄 psychiatry and clinical psychology

Exploring the experiences and support recommendations of autistic adults drinking alcohol

Through semi-structured interviews with 18 autistic adults analyzed via reflexive thematic analysis, this study explores how autistic traits influence alcohol use for social facilitation and self-medication while identifying specific support recommendations to address the unique pressures and coping mechanisms within this community.

Page, S., Easey, K., Sedgewick, F., Rai, D., Stergiakouli, E.2026-08-14
📄 psychiatry and clinical psychology

AVATAR therapy for distressing auditory hallucinations: mediators of change in AVATAR1, a single blind randomised control trial with supportive counselling as active control

This study demonstrates that in a randomized controlled trial, AVATAR therapy reduces the severity, frequency, and distress of auditory hallucinations primarily by decreasing perceived voice omnipotence and increasing assertiveness, agency, and acceptance, rather than through changes in anxiety, self-esteem, or voice malevolence.

Fornells-Ambrojo, M., Ster, A. C., Garety, P., Craig, T. K., Huckvale, M., Emsley, R., Edwards, C., Hardy, A., Ward, T. (…)2026-08-13
📄 psychiatry and clinical psychology

Gambling disorder symptom severity and mental health: an item-response-theory analysis of DSM-5 criteria for gambling disorder

Using item response theory on two large German datasets, this study confirms the hierarchical severity of DSM-5 gambling disorder criteria and reveals that atypical symptom response patterns are associated with poorer mental health, raising important questions about the validity of current diagnostic scoring and practices.

Vogl, F., Wolff, H.-G., Buth, S., Peters, J.2026-08-13
📄 psychiatry and clinical psychology

Acceptability and implementation of digital mental health supports for marginalised young people across Ireland: A mixed-methods study

This mixed-methods study evaluating 11 digital mental health tools among marginalised young people in Ireland found that while digital literacy was high, successful implementation depends on overcoming usability barriers and ensuring tools are trustworthy, culturally relevant, and co-designed with youth to meet their specific emotional and engagement needs.

Kealy, C., Mc Loughlin, A., Madrid-Cagigal, A., O'Neill, S., Donohoe, G., Mulvenna, M. D., Barry, M. M.2026-08-11
📄 psychiatry and clinical psychology

Longitudinal real-world treatment and hospitalisation dynamics in relation to genetic liability across primary psychotic disorders and bipolar disorder

Using real-world data from the Estonian Biobank, this study demonstrates that while genetic liability influences healthcare contact patterns in primary psychotic and bipolar disorders, pharmacological treatment remains the strongest predictor of reduced rehospitalisation risk.

Haring, L., Kolde, A., Pius, M. J., Sonajalg, H., Estonian Biobank Research Team,, Fischer, K., Kasela, S., Mols, M., Al (…)2026-08-07
📄 psychiatry and clinical psychology

WITHDRAWN: The Effectiveness of Mindfulness-Based Cognitive Therapy for Children (MBCT-C) in Internalizing and Externalizing Symptoms and Attention Problems among Children living in Single-Parent Families

The manuscript titled "The Effectiveness of Mindfulness-Based Cognitive Therapy for Children (MBCT-C) in Internalizing and Externalizing Symptoms and Attention Problems among Children living in Single-Parent Families" has been withdrawn by the authors due to the need for substantial revisions and major changes to the study design.

Jamali, S., Rahimian-Boogar, I., Habibi Asgarabad, M.2026-08-05